Careers at Nightbox
We are building a single-construct gene therapy platform with high autonomy per person, AI-augmented R&D infrastructure, and a clear line to first-in-human within 24 months. If that resonates, we should talk.
Open roles
Wet-Lab Scientific Lead
Q2 2026 · Casper, Wyoming or remote-with-travel
Own in vivo validation in three syngeneic murine tumor models. AAV / gene therapy / mouse oncology experience required. Co-author the IND. Founding scientific team equity.
Regulatory / Pre-IND Lead (contract or full-time)
H2 2026
Drive pre-IND meeting prep, FDA briefing book, gene therapy IND assembly. Ex-FDA RMAT reviewer experience strongly preferred.
AI Infrastructure Engineer
Open
Extend the production Claude-based agent stack that drives construct design, freedom-to-operate, and competitive intelligence. Vercel Edge, TypeScript, prompt engineering, biology curiosity.
General interest
If your skill set isn't on this list and you still feel a strong fit, send us a paragraph and a one-page CV at careers@nightboxllc.com. We respond to every well-targeted note.
How we work
- Founder-mode autonomy. Few meetings. Outcomes, not hours.
- AI-augmented loop. Every team member operates a Claude-based research agent.
- Full optionality. Equity participation in clinical milestones.
- Open source where safe. Preprints, methods, and most R&D infrastructure are public.